Myocardial Stress Perfusion MRI Using Regadenoson: A Weight-based Approach in Infants and Young Children

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

Stress perfusion cardiac MRI with regadenoson and gadofoveset trisodium

Background Stress perfusion cardiac MRI (CMR) with a high relaxivity blood-pool contrast agent should allow for improved quantification of myocardial perfusion and myocardium blood volume in patients with coronary artery disease (CAD). In the current study, we sought to evaluate the diagnostic performance and image quality of stress perfusion CMR using the intravascular contrast agent gadofoves...

Detection of obstructive coronary artery disease using regadenoson stress and 82Rb PET/CT myocardial perfusion imaging.

UNLABELLED Our objective was to study the diagnostic performance of regadenoson (82)Rb myocardial perfusion PET imaging to detect obstructive coronary artery disease (CAD). METHODS We studied 134 patients (mean age, 63 ± 12 y; mean body mass index, 31 ± 9 kg/m(2)) without known CAD (96 with coronary angiography and 38 with low pretest likelihood of CAD). Stress left ventricular ejection fract...

Optimal timing of rest perfusion with regadenoson stress testing - normal volunteer study of quantitative MRI perfusion

Methods Seventeen healthy normal volunteers with Framingham score less than 1% underwent vasodilator stress testing with regadenoson using a SSFP sequence. Rest imaging (Rest 1) was performed initially. Twenty minutes later, regadenoson 400mcg was administered as a 10 second injection with saline flush. Stress imaging was done 70 seconds after the injection. All volunteers received aminophyllin...

Regadenoson: a new myocardial stress agent.

Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the U.S. In 2008, the Food and Drug Administration approved regadenoson for stress testing in conjunction with MPI. Regadenoson, unlike adenosine, is a selective A(2A) agonist that is given as an intravenous bolus at a fixed dose, with less undesirable side effects including atrio...